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Search Result

Search Results for " insulin secretion "

20

Compounds

Cat No. Product Name Synonyms Targets
T8348 Phentolamine Adrenergic Receptor
Phentolamine mesylate is an alpha-1 and alpha-2 selective adrenergic receptor antagonist
T7127 DC260126 Apoptosis , GPR
DC260126 is a small-molecule antagonist of FFA1 (GPR40)
T3171 GSK137647A GSK 137647 GPR
GSK137647A (GSK 137647) is a selective FFA4 agonist.
T21623 AS1269574 AS 1269574 GPR , TRP/TRPV Channel
AS1269574 is a potent, orally available GPR119 agonist. AS1269574(AS 1269574) has the potential for the research of type 2 diabetes.
T40187 GNF2133 DYRK
GNF2133 is an effective and selective inhibitor of DYRK1A with IC50s of 6.2 nM. GNF2133 can be used in studies about type 1 diabetes.
T1286 Vincamine Angiopac,Oxybral,Devincan,Novicet,Equipur,Perval GPR , Others
Vincamine (Perval) is a major alkaloid of Vinca minor L., Apocynaceae. It has been used therapeutically as a vasodilator and antihypertensive agent, particularly in cerebrovascular disorders.
T15247 ESI-05 NSC 116966 cAMP
ESI-05 (NSC-116966) is a specific EPAC2 (exchange protein directly activated by cAMP 2) antagonist (IC50: 0.4 μM). ESI-05 inhibits cAMP-mediated activation of EPAC2, as well as EAPC2, mediated Rap1 activation.
T2755 Rhoifolin Apigenin-7-O-rhamnoglucoside,Apigenin 7-O-neohesperidoside,Rhoifoloside Others , p38 MAPK , NF-κB , transporter , IGF-1R , Autophagy
Rhoifolin (Apigenin 7-O-neohesperidoside) is extracted from Turpinia arguya Seem dried leaves.
TP1376 GLP-1(7-37) acetate(106612-94-6 free base) GLP-1(7-37) acetate Others , Glucagon Receptor
Glp-1(7-37) acetate is an intestinal insulin hormone that enhances glucose-induced insulin secretion.
TP1382L HAEGTFTSDVS acetate HAEGTFTSDVS acetate(864915-61-7 free base) Glucagon Receptor
HAEGTFTSDVS acetate is the first N-terminal 1-11 residues of GLP-1 which stimulates insulin secretion from pancreatic β-cells.
TP2017L GIP (1-39) acetate GIP (1-39) acetate(725474-97-5 Free base) Others
GIP (1-39) acetate is a gastric inhibitory peptide (GIP) purified from porcine intestine and stimulates insulin secretion.
T3984 GLP-1(7-36), amide MKC 253,Human GLP-1-(7-36)-amide,Glucagon-like Peptide 1 (7-36) amide,Glucagon-Like Peptide (GLP) I (7-36), amide, human,GLP-1(7-36),GLP-1-(7-36)-amide Glucagon Receptor
GLP-1(7-36), amide (MKC 253) is a peptide hormone released from intestinal L-cells upon nutrient consumption. It binds the GLP-1 receptor in the pancreas and displays various antidiabetic effects by potentiating glucose-...
TP1863L Glucagon (19-29), human acetate Glucagon Receptor
Glucagon (19-29), human acetate a COOH-terminal fragment processed from glucagon, is a potent and efficient inhibitor of insulin secretion.
T31976 Glymidine sodium Others
Glymidine sodium is a sulfonamide hypoglycemic agent which stimulates insulin secretion.
T4S0295 Apigenin 7-glucoside Cosmetin,Cosmosiin,Cosmosioside,Apigenin-7-O-β-D-glucopyranoside,Thalictiin,Apigetrin Reactive Oxygen Species , HIV Protease
1. Apigenin 7-glucoside (Cosmosiin) is a anti-HIV agent. 2. Cosmosiin may be beneficial for diabetic complications through their enhanced adiponectin secretion, tyrosine phosphorylation of insulin receptor-β and GLUT4 tr...
TP2018L GIP (human) acetate GIP (human) acetate(100040-31-1 Free base) IGF-1R
GIP (human) acetate is a stimulator of glucose-dependent insulin secretion and a weak inhibitor of gastric acid secretion. GIP (human) acetate plays a vital role in lipid metabolism and the development of obesity.
T1088 Repaglinide AG-EE 388 ZW,AG-EE 623ZW Potassium Channel , PPAR
Repaglinide (AG-EE 623ZW) is a benzoic acid derivative that stimulates insulin secretion from the pancreas and is used in the therapy of type 2 diabetes. Repaglinide has been linked to rare instances of clinically appare...
T2740 Trans-Cinnamic acid Isocinnamic acid,Cinnamic acid,trans-3-Phenylacrylic acid,Phenylacrylic acid,Cinnamylic acid,3-Phenylacrylic acid,Myricitrine Endogenous Metabolite , Antibacterial
trans-Cinnamic acid (Myricitrine) exerts anti-diabetic activity by improving glucose tolerance in vivo and by stimulating insulin secretion in vitro.
T1781 GW9508 GW 9508 GPR , Potassium Channel
GW9508(GW 9508) is a potent and selective agonist for FFA1 (GPR40), stimulates insulin secretion in a glucose-sensitive manner.
T2P2919 (2S,3R,4S)-4-Hydroxyisoleucine (4S)-4-Hydroxy-L-isoleucine,Hydroxyisoleucine PI3K
(2S,3R,4S)-4-Hydroxyisoleucine (Hydroxyisoleucine) from fenugreek (Trigonella foenum-graecum) seeds is a potential insulinotropic (anti-diabetic) and anti-obesity amino acid. HIL stimulates glucose-dependent insulin secr...

Compounds

Phentolamine
T8348
Synonym:
Target: Adrenergic Receptor
DC260126
T7127
Synonym:
Target: Apoptosis, GPR
GSK137647A
T3171
Synonym: GSK 137647
Target: GPR
AS1269574
T21623
Synonym: AS 1269574
Target: GPR, TRP/TRPV Channel
GNF2133
T40187
Synonym:
Target: DYRK
Vincamine
T1286
Synonym: Angiopac,Oxybral,Devincan,Novicet,Equipur,Perval
Target: GPR, Others
ESI-05
T15247
Synonym: NSC 116966
Target: cAMP
Rhoifolin
T2755
Synonym: Apigenin-7-O-rhamnoglucoside,Apigenin 7-O-neohesperidoside,Rhoifoloside
Target: Others, p38 MAPK, NF-κB, transporter, IGF-1R, Autophagy
GLP-1(7-37) acetate(106612-94-6 free base)
TP1376
Synonym: GLP-1(7-37) acetate
Target: Others, Glucagon Receptor
HAEGTFTSDVS acetate
TP1382L
Synonym: HAEGTFTSDVS acetate(864915-61-7 free base)
Target: Glucagon Receptor
GIP (1-39) acetate
TP2017L
Synonym: GIP (1-39) acetate(725474-97-5 Free base)
Target: Others
GLP-1(7-36), amide
T3984
Synonym: MKC 253,Human GLP-1-(7-36)-amide,Glucagon-like Peptide 1 (7-36) amide,Glucagon-Like Peptide (GLP) I (7-36), amide, human,GLP-1(7-36),GLP-1-(7-36)-amide
Target: Glucagon Receptor
Glucagon (19-29), human acetate
TP1863L
Synonym:
Target: Glucagon Receptor
Glymidine sodium
T31976
Synonym:
Target: Others
Apigenin 7-glucoside
T4S0295
Synonym: Cosmetin,Cosmosiin,Cosmosioside,Apigenin-7-O-β-D-glucopyranoside,Thalictiin,Apigetrin
Target: Reactive Oxygen Species, HIV Protease
GIP (human) acetate
TP2018L
Synonym: GIP (human) acetate(100040-31-1 Free base)
Target: IGF-1R
Repaglinide
T1088
Synonym: AG-EE 388 ZW,AG-EE 623ZW
Target: Potassium Channel, PPAR
trans-Cinnamic acid
T2740
Synonym: Isocinnamic acid,Cinnamic acid,trans-3-Phenylacrylic acid,Phenylacrylic acid,Cinnamylic acid,3-Phenylacrylic acid,Myricitrine
Target: Endogenous Metabolite, Antibacterial
GW9508
T1781
Synonym: GW 9508
Target: GPR, Potassium Channel
(2S,3R,4S)-4-Hydroxyisoleucine
T2P2919
Synonym: (4S)-4-Hydroxy-L-isoleucine,Hydroxyisoleucine
Target: PI3K
1 2 3 4 5 6
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